Thermo Fisher Scientific TNF alpha Monoclonal Antibody (VPM61)
양 TNF alpha를 인식하는 마우스 단클론 항체(VPM61)로, Western blot, IHC, Flow cytometry, ELISA에 사용 가능. 단백질 A로 정제된 액상 항체이며, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Sheep |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VPM61 |
| Immunogen | Recombinant ovine TNF alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745472 |
Product Specific Information
Mouse anti-Sheep TNF alpha, clone VPM61 recognizes ovine tumor necrosis factor (TNF) alpha, a 17 kDa cytokine.
Target Information
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is mainly secreted by macrophages and binds to receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. TNF alpha regulates immune responses, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. It typically forms multimers and appears as a 17 kDa band under non-reducing SDS-PAGE conditions. TNF alpha plays roles in immune defense, tumor necrosis, and has been implicated in autoimmune diseases, insulin resistance, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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