Thermo Fisher Scientific Aurora A Polyclonal Antibody
Aurora A 단백질을 인식하는 Rabbit Polyclonal 항체로, ICC/IF 실험에 적합합니다. 0.25 mg/mL 농도의 액상 형태로 제공되며, 4°C에서 보관합니다. 여러 영장류 종과 교차 반응이 예측되며, 암 연구 및 세포주기 조절 연구에 활용 가능합니다.
- 카탈로그번호
- IHC00062x (2개 옵션)
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 75–125 of Aurora A (UniProt ID: O14965-1, antigen length: 403 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Gorilla, Chimpanzee, and Northern white-cheeked gibbon.
Target Information
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, related to centrosome/spindle pole function during chromosome segregation. It plays a key role in tumor development and progression and is overexpressed in cancers such as breast, ovarian, and colorectal. Aurora A is considered a potential target for anticancer drug development.
Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus, and spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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