ELK Biotechnology FGF-13 rabbit pAb
FGF-13 rabbit pAb는 인간, 생쥐, 랫트에서 반응하는 다클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 FGF13 유래 합성 펩타이드로 면역생성되었으며, 세포 내 핵 및 세포질 위치에서 발현되는 단백질 검출에 활용됩니다. 고순도 IgG 형식으로 안정적 보관이 가능합니다.
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제품명
FGF-13 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | FGF13; FHF2; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FGF13. AA range: 154-203 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 28 kD |
| Gene ID (Human) | 2258 |
| Human Swiss-Prot No | Q92913 |
| Species Reactivity | Human; Mouse; Rat |
세포 내 위치
- Isoform 1: Nucleus
- Isoform 2: Cytoplasm, Nucleus
- Isoform 3: Cytoplasm, Nucleus
- Isoform 4: Cytoplasm, Nucleus
- Isoform 5: Cytoplasm, Nucleus
- Cell projection: filopodium, growth cone, dendrite
- Cell membrane: sarcolemma
- Cytoplasm
- Not secreted
- Localizes to the lateral membrane and intercalated disks of myocytes
배경 정보
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
This gene is located on chromosome X, associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of BFLS and other X-linked mental retardation forms.
Alternative splicing at the 5' end results in several transcript variants encoding different isoforms with distinct N-termini.
[provided by RefSeq, Nov 2008]
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