ELK Biotechnology EphA3 rabbit pAb
EphA3 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간, 마우스, 랫트에서 반응하며, 세포막 및 분비형 단백질 검출에 유용합니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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제품명
EphA3 rabbit pAb
제품 개요
EphA3 단백질을 타깃으로 하는 토끼 다클론 항체입니다. Ephrin receptor 패밀리에 속하며, 신경계 발달 및 세포 신호전달 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | EphA3 rabbit pAb |
| Alternative Names | EPHA3; ETK; ETK1; HEK; TYRO4; Ephrin type-A receptor 3; EPH-like kinase 4; EK4; hEK4; HEK; Human embryo kinase; Tyrosine-protein kinase TYRO4; Tyrosine-protein kinase receptor ETK1; Eph-like tyrosine kinase 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from EphA3 (AA range: 540-620) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100 kD |
| Gene ID (Human) | 2042 |
| Human Swiss-Prot No. | P29320 |
| Cellular Localization | Isoform 1: Cell membrane (Single-pass type I membrane protein) Isoform 2: Secreted |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a cysteine-rich domain and two fibronectin type III repeats. The ephrin receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. (RefSeq, Jul 2008)
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