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ELK Biotechnology 4E-BP1 (phospho Thr70) rabbit pAb
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인간, 생쥐, 랫트 시료에 반응하는 4E-BP1 (phospho Thr70) rabbit polyclonal antibody. IHC, IF, ELISA에 적합하며, Thr70 인산화 부위를 인식. 고순도 IgG, -20°C에서 1년 보관 가능.
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- pk
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ELK Biotechnology ES5079-100UL 4E-BP1 (phospho Thr70) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES5079-50UL 4E-BP1 (phospho Thr70) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology 4E-BP1 (phospho Thr70) rabbit pAb
제품명
4E-BP1 (phospho Thr70) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EIF4EBP1; Eukaryotic translation initiation factor 4E-binding protein 1; 4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human 4E-BP1 around the phosphorylation site of Thr70 (AA range: 36–85) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 1978 |
| Human Swiss-Prot No. | Q13541 |
| Cellular Localization | Nucleoplasm, cytoplasm, cytosol, protein complex |
| Species Reactivity | Human; Rat; Mouse |
Background
Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) is a translation repressor protein that interacts directly with eukaryotic translation initiation factor 4E (eIF4E), a key component in recruiting 40S ribosomal subunits to the 5′ end of mRNAs. This interaction inhibits complex assembly and represses translation. The protein is phosphorylated in response to various stimuli, including UV irradiation and insulin signaling, leading to its dissociation from eIF4E and activation of mRNA translation.
(Information provided by RefSeq, Jul 2008)
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