ELK Biotechnology CRMP-2 (phospho Ser522) rabbit pAb
CRMP-2 (phospho Ser522) rabbit pAb는 신경세포 성장 및 극성 연구에 적합한 인산화 특이 항체입니다. Western blot과 ELISA에 사용 가능하며, 인간, 생쥐, 랫트 시료에 반응합니다. 고순도 IgG 폴리클로날 항체로 -20°C에서 1년간 안정적으로 보관됩니다.
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제품명
CRMP-2 (phospho Ser522) rabbit pAb
공급업체
ELK Biotechnology
제품 설명
CRMP-2 (phospho Ser522) rabbit pAb는 인간 CRMP-2 단백질의 Ser522 인산화 부위를 인식하는 폴리클로날 항체입니다. 신경세포의 성장, 극성 및 시냅스 신호전달에 관련된 연구에 활용됩니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Alternative Names | DPYSL2; CRMP2; ULIP2; Dihydropyrimidinase-related protein 2; DRP-2; Collapsin response mediator protein 2; CRMP-2; N2A3; Unc-33-like phosphoprotein 2; ULIP-2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human CRMP-2 (phospho Ser522) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 62 kD |
| GeneID (Human) | 1808 |
| Human Swiss-Prot No | Q16555 |
| Cellular Localization | Cytoplasm, cytosol; Cytoplasm, cytoskeleton; Membrane; Tightly but non-covalently associated with membranes |
| Species Reactivity | Human; Mouse; Rat |
배경 정보
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer’s disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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