
ELK Biotechnology Cystatin E/M rabbit pAb
Cystatin E/M 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 적합합니다. 인간, 랫드, 마우스 시료에 반응하며, 내부 펩타이드 유래 면역원으로 제작되었습니다. -20°C에서 1년 보관 가능합니다.
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Cystatin E/M rabbit pAb
제품 개요
Cystatin E/M 단백질을 인식하는 토끼 폴리클로날 항체입니다. 인간, 랫드, 마우스 시료에서 사용 가능하며, 다양한 면역학적 분석(IHC, IF, ELISA)에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cystatin E/M rabbit pAb |
| Alternative Names | CST6; Cystatin-M; Cystatin-6; Cystatin-E |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100 - 1/300 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human Cystatin E/M |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 1474 |
| Human Swiss-Prot No | Q15828 |
| Cellular localization | Secreted |
| Species Reactivity | Human; Rat; Mouse |
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and the kininogens.
The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions.
This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.
[provided by RefSeq, Jul 2008]
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