ELK Biotechnology c-Fms (phospho Tyr809) rabbit pAb
인간 M-CSF 수용체의 Tyr809 인산화 부위를 인식하는 rabbit polyclonal antibody. WB와 ELISA에 적합하며, 세포막 단백질 검출에 사용. 인산화 신호전달 연구 및 CSF1R 관련 질환 연구에 유용.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology c-Fms (phospho Tyr809) rabbit pAb
제품명
c-Fms (phospho Tyr809) rabbit pAb
제품 개요
이 항체는 인간 M-CSF Receptor의 Tyr809 인산화 부위를 기반으로 제작된 rabbit polyclonal antibody입니다. CSF1R 신호전달 연구 및 관련 질환 연구에 활용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | c-Fms (phospho Tyr809) rabbit pAb |
| Alternative Names | CSF1R; FMS; Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD antigen CD115 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human M-CSF Receptor around the phosphorylation site of Tyr809 (AA range: 781–830) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 108 kDa |
| Gene ID (Human) | 1436 |
| Human Swiss-Prot No. | P07333 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is the receptor for colony stimulating factor 1 (CSF1), a cytokine that controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of CSF1. Ligand binding activates the receptor kinase through oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and a member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with predisposition to myeloid malignancy. The first intron contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. (RefSeq, Dec 2013)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.