Thermo Fisher Scientific Alcohol Dehydrogenase 1C Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ELISA에 적합. ADH1C 단백질(aa 1-375)에 대한 고특이성 항체. 액상 형태로 0.55 mg/mL 농도, -20°C 보관. Cytoplasm 내 ADH1C 검출에 유용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–375 of human ADH1C (NP_000660.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914746 |
Product Specific Information
- Positive test controls: A-549, HepG2, 293T
- Subcellular localization: Cytoplasm
Immunogen sequence:
MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAAGICRSD EHVVSGNLVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLFTPQCGK CRICKNPESN YCLKNDLGNP RGTLQDGTRR FTCSGKPIHH FVGVSTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVKVAKV TPGSTCAVFG LGGVGLSVVM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSINPMLLL TGRTWKGAIF GGFKSKESVP KLVADFMAKK FSLDALITNI LPFEKINEGF DLLRSGKSIR TVLTF
Target Information
This gene encodes class I alcohol dehydrogenase, gamma subunit, a member of the alcohol dehydrogenase family. These enzymes metabolize ethanol, retinol, aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.
Class I alcohol dehydrogenase forms homo- and heterodimers (alpha, beta, gamma subunits) with high ethanol oxidation activity, playing a major role in ethanol catabolism.
The three genes encoding alpha, beta, and gamma subunits are tandemly organized in a genomic cluster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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