Thermo Fisher Scientific HIF-2 alpha Monoclonal Antibody (GT1689)
인간 HIF-2 alpha 단백질을 인식하는 Mouse IgG1 단클론 항체로, ICC/IF에 사용 가능. Protein G로 정제된 액상 형태이며, PBS 버퍼에 보존제 없이 제공. 예측 반응종은 Mouse와 Pig로, 산소 조절 관련 유전자 연구에 적합.
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Thermo Fisher Scientific HIF-2 alpha Monoclonal Antibody (GT1689)
Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1689 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human HIF-2 alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.43 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787156 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (80%), Pig (83%).
- Centrifuge briefly prior to opening the vial.
Target Information
HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen.
It contains a basic-helix-loop-helix domain and a protein dimerization domain, participating in oxygen-sensing signal transduction pathways.
HIF-2 alpha regulates vascular endothelial growth factor (VEGF) expression and plays a role in blood vessel and lung tubular system development.
Mutations in this gene are associated with erythrocytosis familial type 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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