Thermo Fisher Scientific Septin 9 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from the date of receipt.

Target Information

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses: large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs that allow homo- and heterodimerization with other bZip transcription factors. Large Mafs contain an acidic transactivation domain absent in small Maf proteins. Although small Maf proteins lack inherent transactivation activity, they can act as positive or negative regulators of transcription by interacting with transcriptional activators or repressors.

Human MafF was isolated from a human myometrium cDNA library and encodes a 164 amino acid protein. Like other small Maf proteins, it contains an extended leucine zipper structure but lacks an N-terminal transactivating domain. The three small Maf proteins are involved in various physiological processes, including development, differentiation, hematopoiesis, and stress response, each through distinct mechanisms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.