Thermo Fisher Scientific Septin 9 Polyclonal Antibody
Thermo Fisher Scientific의 Septin 9 Polyclonal Antibody는 인간 단백질에 반응하는 토끼 IgG 항체로, Western blot, IHC, IP 등 다양한 응용에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 536 and 586 of Human Septin 9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses: large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs that allow homo- and heterodimerization with other bZip transcription factors. Large Mafs contain an acidic transactivation domain absent in small Maf proteins. Although small Maf proteins lack inherent transactivation activity, they can act as positive or negative regulators of transcription by interacting with transcriptional activators or repressors.
Human MafF was isolated from a human myometrium cDNA library and encodes a 164 amino acid protein. Like other small Maf proteins, it contains an extended leucine zipper structure but lacks an N-terminal transactivating domain. The three small Maf proteins are involved in various physiological processes, including development, differentiation, hematopoiesis, and stress response, each through distinct mechanisms.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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