Thermo Fisher Scientific Phospho-Bcl-3 (Ser41) Polyclonal Antibody
Phospho-Bcl-3 (Ser41) 특이적 인식 항체로 인간 및 생쥐 시료에 적용 가능. Western blot 및 IHC(P)에서 사용 가능. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포 내 BCL-3 Ser41 인산화 상태 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL3 (Accession P20749), corresponding to amino acid residues around phosphorylated Ser41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816953 |
Product Specific Information
This antibody detects endogenous levels of BCL-3 only when phosphorylated at Ser41.
Target Information
B cell Lymphoma 3 (BCL-3) is a member of the IκB subfamily of inhibitors, which are part of the NF-κB transcription factor family. A balance among NF-κB family members regulates apoptosis and survival of activated T cells. BCL-3 exhibits versatile functions including:
- Cytoplasmic activation of p50 homodimers
- Nuclear translocation
- Modulation of transcriptional machinery within the nucleus
BCL-3 activity depends on interactions with nuclear proteins such as Tip60, Jab1, Bard1, and Pirin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-105525_BCL-3_P20749-1_Rabbit.svg, PA5-105525_BCL-3_P20749-1_Rabbit_PDP.jpeg)
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