Thermo Fisher Scientific SOX-2 Polyclonal Antibody
SOX-2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 다양한 종에 반응하며, WB, IHC, ICC/IF 등 응용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 안정화제 포함 PBS 버퍼에 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:250 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from N-terminus of Human SOX-2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse embryonic brain
- Cellular location: Nuclear
Target Information
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in embryonic development and cell fate determination. SOX2 is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach. The gene lies within an intron of SOX2 overlapping transcript (SOX2OT). SOX2 protein may act as a transcriptional activator by forming complexes with other proteins. Mutations in SOX2 are associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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