Thermo Fisher Scientific RAB3d Polyclonal Antibody
Rabbit polyclonal antibody targeting Human RAB3d protein. Recombinant immunogen-based antibody for research use only. Supplied as liquid form at 0.1 mg/mL concentration. Suitable for detecting Rab3D in various tissues such as tongue, pancreas, and liver.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RAB3d |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662307 |
Product Specific Information
Immunogen sequence:
CEKMNESLEPS SSSGSNGKGP AVGDAPAPQP SSCSC
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 83%
Target Information
Rab proteins are low-molecular-weight GTP-binding proteins forming the largest branch of the Ras superfamily of GTPases. They are located on the cytoplasmic face of organelles and vesicles and are involved in intracellular membrane fusion reactions.
Three membrane proteins — synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin — form the core of a ubiquitous membrane fusion machine that interacts with soluble proteins N-ethylmaleimide-sensitive factor (NSF) and α-SNAP.
Rab proteins, together with the core fusion machinery and Munc-18, mediate vesicle docking and fusion. Over 40 rab proteins have been described in mammals. Rab3D is present, in part, in the tongue, pancreas, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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