Thermo Fisher Scientific H4K20me2 Polyclonal Antibody
H4K20me2에 특이적인 Rabbit Polyclonal 항체로 다양한 종에 반응. Western blot에 최적화되어 있으며 항원 친화 크로마토그래피로 정제됨. 보존제 없이 -20°C에서 보관. H3 메틸화 히스톤과 교차 반응 없음.
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Thermo Fisher Scientific H4K20me2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, C. elegans, Fruit fly, Horse, Human, Mouse, Non-human primate, Pig, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the amino terminus of histone H4 in which lysine 20 is di-methylated |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980676 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with mono-, di-, or tri-methylated histone H3 at Lys4, Lys9, Lys27, or Lys36.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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