Thermo Fisher Scientific MRPS18B Polyclonal Antibody
Human MRPS18B 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(P), ICC/IF에 적합. 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며, 단기 4°C, 장기 -20°C 저장 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPS18B. Recombinant protein control fragment (Product #RP-100644). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644185 |
Product Specific Information
Immunogen sequence:
GLLIYHIPQV EPRDLDFSTS HGAVSATPPA PTLVSGDPWY PWYNWKQPPE RELSRLRRLY QGHLQEESGP PPESMPKMP
Highest antigen sequence identity to orthologs:
- Mouse: 82%
- Rat: 80%
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are essential for protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome differ greatly among species, making sequence homology recognition difficult.
This gene encodes a 28S subunit protein of the ribosomal protein S18P family. It is one of three human mitochondrial S18 proteins showing sequence similarity to bacterial S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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