
Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI1H2), TrueMAB
인간 F13A1 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ICC/IF에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며, 재구성 후 1 mg/mL 농도로 실험 가능합니다.
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Thermo Fisher Scientific F13A1 Monoclonal Antibody (OTI1H2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H2 |
| Immunogen | Full-length human recombinant protein of human F13A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes the coagulation factor XIII A subunit, the last zymogen activated in the blood coagulation cascade. Plasma factor XIII consists of two A subunits with catalytic function and two B subunits that act as carrier molecules. Platelet factor XIII contains only A subunits identical to plasma origin. Upon activation by thrombin and calcium ions, the B subunits dissociate, yielding the active enzyme factor XIIIa.
Factor XIIIa catalyzes crosslinking between fibrin molecules, stabilizing the clot, and also crosslinks alpha-2-plasmin inhibitor or fibronectin to fibrin.
Deficiency of factor XIII can lead to bleeding disorders, impaired wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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