Thermo Fisher Scientific CCR8 Recombinant Rabbit Monoclonal Antibody (ARC0956)
CCR8 단백질을 인식하는 토끼 단클론 항체로, Western blot, ICC/IF, ELISA에 사용 가능. 인간 및 생쥐 반응성. HEK293 세포에서 발현된 재조합 항체로 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0956 |
| Immunogen | Synthetic peptide corresponding to amino acids 250–355 of human CCR8 (UniProt ID: P51685) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849377 |
Product Specific Information
Immunogen sequence:
FWVPFNVVLF LTSLHSMHIL DGCSISQQLT YATHVTEIIS FTHCCVNPVI YAFVGEKFKK HLSEIFQKSC SQIFNYLGRQ MPRESCEKSS SCQQHSSRSS SVDYIL
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven-transmembrane G protein-coupled receptor. Chemokines and their receptors play crucial roles in directing cell migration to inflammatory sites. CCR8 is preferentially expressed in the thymus, with known ligands including I-309, TARC, and MIP-1β. This receptor is implicated in monocyte chemotaxis regulation, thymic cell apoptosis, and positioning of activated T cells within antigenic challenge sites and lymphoid tissues. Expression has been observed in spleen, thymus, NK cells, monocytes, and T cells, with lower levels in peripheral blood leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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