Thermo Fisher Scientific EWSR1 Monoclonal Antibody (OTI3F6)

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The EWSR1 gene encodes a multifunctional protein involved in gene expression, cell signaling, RNA processing, and transport. It contains an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain.
Chromosomal translocations between EWSR1 and other transcription factor genes lead to chimeric proteins implicated in tumorigenesis, including Ewing sarcoma, neuroectodermal tumors, and other malignancies.
Alternative splicing produces multiple transcript variants, and related pseudogenes are found on chromosomes 1 and 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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