Thermo Fisher Scientific P75ntr Monoclonal Antibody (ME20.4)

Applications

Tested Dilution

Publications

Western Blot (WB)

2-5 µg/mL

-

Immunohistochemistry (IHC)

2-5 µg/mL

-

Flow Cytometry (Flow)

2-5 µg/mL

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Dog, Cat, Human, Non-human primate, Pig, Rabbit

Published species

Not Applicable

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

ME20.4

Immunogen

Human melanoma cell lines if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NGFR (CD271),uniProtId:P08138-1,ncbiNodeId:9606,antigenRange:1-427,antigenLength:427,antigenImageFileName:OSM00018A-150UG_NGFR_CD271_P08138-1_House_mouse.svg,antigenImageFileNamePDP:OSM00018A-150UG_NGFR_CD271_P08138-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

Affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: p75NTR.

Target Information

Neurotrophic factors control the survival, differentiation and maintenance of neurons in the peripheral and central nervous systems, and of other neural crest-derived cell types. Developing sympathetic neurons are absolutely dependent upon nerve growth factor (NGF) during the period of target competition in vivo. Antibodies reacting specifically with NGFR p75 are useful tools in the detection and characterization of NGFR p75, to enhance our understanding of a wide range of phenomena in the development, plasticity and repair of the nervous system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.