Thermo Fisher Scientific P75ntr Monoclonal Antibody (ME20.4)
p75NTR 단백질을 인식하는 ME20.4 클론의 Mouse IgG1 단일클론 항체. Western blot, IHC, Flow cytometry에 사용 가능. 인간 및 다양한 종에서 반응. Lyophilized 형태로 제공되며 PBS buffer에 보존. 신경 성장 인자 수용체 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2–5 µg/mL | - |
| Immunohistochemistry (IHC) | 2–5 µg/mL | - |
| Flow Cytometry (Flow) | 2–5 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Dog, Cat, Human, Non-human primate, Pig, Rabbit |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ME20.4 |
| Immunogen | Human melanoma cell lines (target family: NGFR (CD271), UniProt ID: P08138-1, antigen range: 1–427, antigen length: 427) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: p75NTR.
Target Information
Neurotrophic factors control the survival, differentiation, and maintenance of neurons in the peripheral and central nervous systems, and other neural crest-derived cell types. Developing sympathetic neurons depend on nerve growth factor (NGF) during target competition in vivo.
Antibodies specific to NGFR p75 are useful tools for detection and characterization of NGFR p75, aiding in the study of development, plasticity, and repair of the nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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