Thermo Fisher Scientific RAB11FIP1 Monoclonal Antibody (1A12B9D8)
RAB11FIP1 단백질을 표적하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합. Human 및 Mouse 반응성, Protein G 정제, PBS buffer, sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A12B9D8 |
| Immunogen | Purified recombinant fragment of human RAB11FIP1 (AA: 130–271) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787499 |
Product Specific Information
MA5-31876 has been tested in indirect ELISA.
Target Information
Rab11-FIP1 (Rab 11 family-interacting protein 1), also known as Rab-coupling protein (RCP), is a 1283 amino acid Rab 11 effector protein.
By interacting with Rab GTPases, Rab11-FIP1 is involved in the endosomal recycling process and may play a role in controlling membrane trafficking along the phagocytic pathway and during phagocytosis.
Localized to the recycling endosome, cytoplasmic membrane, and phagosome membranes, Rab11-FIP1 is expressed as five isoforms produced by alternative splicing.
Isoform two, the most highly expressed, is found in brain, lung, testis, small intestine, spleen, and heart.
Isoform two forms a homooligomer and interacts with Rab GTPases such as Rab 4A, Rab 11A, Rab 11B, and Rab 25.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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