Thermo Fisher Scientific ERp57 Polyclonal Antibody
ERp57 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로 단백질 접힘 및 ER 관련 연구에 적합.
- 카탈로그번호
- PA585392
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ERp57 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792534 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (92%), Rat (92%), Pig (94%), Rabbit (94%), Chicken (80%), Sheep (91%), Rhesus Monkey (98%), Chimpanzee (100%), Bovine (93%).
- Positive control: HepG2, HCT116, 293T, A431, HeLa, Neuro2A, GL261, C8D30, PC-12, Rat2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins.
Although once thought to be a phospholipase, it has been demonstrated that the protein actually has protein disulfide isomerase activity.
Complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in glycoprotein substrates.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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