Thermo Fisher Scientific VPS51 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human VPS51. Recombinant protein control fragment (Product #RP-107068). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:VPS51,uniProtId:Q9UID3-1,ncbiNodeId:9606,antigenRange:294-376,antigenLength:782,antigenImageFileName:PA5-66395_VPS51_Q9UID3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66395_VPS51_Q9UID3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2665087

Product Specific Information

Immunogen sequence: SPPAPDVLEFT DHGGSGFVGG LCQVAAAYQE LFAAQGPAGA EKLAAFARQL GSRYFALVER RLAQEQGGGD NSLLVRALDR FH

Highest antigen sequence identity to the following orthologs - mouse 93%, rat 93%.

Target Information

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.