
Thermo Fisher Scientific VPS51 Polyclonal Antibody
Thermo Fisher Scientific의 VPS51 Polyclonal Antibody는 인간 VPS51 단백질을 인식하는 토끼 유래 IgG 항체로, ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. GARP 및 EARP 복합체 연구에 적합하며, 액상 형태로 4°C 또는 -20°C에서 안정적으로 보관됩니다.
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Thermo Fisher Scientific VPS51 Polyclonal Antibody
Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human VPS51. Recombinant protein control fragment (Product #RP-107068) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665087 |
Product Specific Information
Immunogen sequence:
SPPAPDVLEFT DHGGSGFVGG LCQVAAAYQE LFAAQGPAGA EKLAAFARQL GSRYFALVER RLAQEQGGGD NSLLVRALDR FH
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
VPS51 acts as a component of the GARP complex, which mediates retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
The GARP complex is essential for:
- Maintenance of protein retrieval from endosomes to the TGN
- Acid hydrolase sorting and lysosome function
- Endosomal cholesterol traffic and autophagy
VPS51 also functions in the EARP complex, involved in endocytic recycling.
The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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