Thermo Fisher Scientific TADA2L Polyclonal Antibody
Recombinant Human TADA2L을 면역원으로 한 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF 실험에 0.25–2 µg/mL로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 단기 4°C·장기 -20°C 보관이 권장됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TADA2L. Recombinant protein control fragment (Product #RP-108086) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662213 |
Product Specific Information
- Immunogen sequence:
MDRLGPFSNDP SDKPPCRGCS SYLMEPYIKC AECGPPPFFL CLQCFTRGFE YKKHQSDHTY EIMTSD - Highest antigen sequence identity to the following orthologs:
- Mouse: 97%
- Rat: 99%
Target Information
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as two alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues.
It contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling.
Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, which exhibits histone acetyltransferase activity on histones H3 and H4.
The gene encoding TADA2L spans 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome, and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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