Thermo Fisher Scientific PRC1 Polyclonal Antibody
Human PRC1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 실험에 적합. 보존제가 없는 액상 형태이며 Protein A 및 Antigen affinity chromatography로 정제됨. 세포분열 관련 PRC1 단백질 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:1,500–1:50,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of Human PRC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788192 |
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human PRC1.
Target Information
This gene encodes a protein involved in cytokinesis. The protein is highly expressed during the S and G2/M phases of mitosis, but its levels drop dramatically when the cell exits mitosis and enters the G1 phase.
It is located in the nucleus during interphase, associates dynamically with mitotic spindles during mitosis, and localizes to the cell mid-body during cytokinesis.
This protein is a substrate of several cyclin-dependent kinases (CDKs) and is necessary for polarizing parallel microtubules and concentrating factors responsible for contractile ring assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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