
Thermo Fisher Scientific HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Monoclonal Antibody (SPM253)
HSP60 미토콘드리아 마커 단일클론 항체로 다양한 종에 반응. Western blot, IHC, ICC, Flow cytometry에 적합. 단백질 접힘 및 미토콘드리아 단백질 조립 연구용. 비세균성 교차반응 없음. 연구용 전용 제품.
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Thermo Fisher Scientific HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) Monoclonal Antibody (SPM253)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Fruit fly, Hamster, Human, Mouse, Non-human primate, Sheep, Pig, Rabbit, Rat, Xenopus |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SPM253 |
| Immunogen | Recombinant human HSP60 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with bacteria, helminths, or spinach.
Target Information
The HSP60 gene encodes a mitochondrial chaperonin protein that assists in the folding and assembly of newly imported proteins within mitochondria. It may also act as a signaling molecule in the innate immune system. The gene is located adjacent to a related family member, with the intergenic region functioning as a bidirectional promoter. Several pseudogenes are associated with this gene, and two transcript variants encoding the same protein have been identified. Mutations in this gene are linked to autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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