Thermo Fisher Scientific Phospho-GluA4 (Ser862) Polyclonal Antibody
Phospho-GluA4 (Ser862) 특이적 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Rabbit IgG 기반의 액상형 항체이며, Protein A로 정제됨. GluA4 단백질의 Ser862 인산화 부위를 인식하여 신경전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human GluA4 around the phosphorylation site of Ser862 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development, and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR1 to GluR7. These receptors are primarily responsible for fast excitatory neurotransmission by glutamate, whereas NMDA receptors are characterized by slower kinetics and higher Ca²⁺ permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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