Thermo Fisher Scientific HGF Monoclonal Antibody (OTI3F2), TrueMAB
HGF 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, Western Blot 및 IHC(P) 실험에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol buffer 구성, -20°C 보관 조건을 권장합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 200–494 of human HGF produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hepatocyte Growth Factor (HGF) regulates cell growth, motility, and morphogenesis via activation of the c-Met receptor tyrosine kinase signaling cascade. It is secreted by mesenchymal cells and functions as a multi-functional cytokine on epithelial cells. HGF plays a key role in angiogenesis, tumorogenesis, and tissue regeneration. The inactive precursor is cleaved into a 69-kDa alpha-chain and a 34-kDa beta-chain, forming an active heterodimer linked by a disulfide bond. Although belonging to the plasminogen subfamily of S1 peptidases, it lacks protease activity. Multiple transcript variants are generated by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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