Thermo Fisher Scientific ARNT2 Polyclonal Antibody
ARNT2 단백질의 내인성 수준을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 인간, 마우스, 랫트에 반응하며 Western blot 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 용액 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARNT2 (Accession Q9HBZ2), corresponding to amino acid residues T30–T80 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850702 |
Product Specific Information
Antibody detects endogenous levels of total ARNT2.
Target Information
AhR, ARNT1, ARNT2, and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common PAS motif.
The aromatic (aryl) hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that interacts with xenobiotic responsive elements (XREs) to activate genes such as CYP1A1, glutathione S-transferase Ya subunit, and DT-diaphorase.
Ah receptor nuclear translocator proteins (ARNT1 and ARNT2) are required for ligand-dependent nuclear translocation of AhR and necessary for AhR binding to the XRE element.
BMAL1 (Brain and Muscle Arnt-like protein 1), also known as Arnt3, TIC, JAP3, or MOP-3, dimerizes with Clock and binds to the promoter region of mPer1, playing a role in circadian rhythm regulation in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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