Thermo Fisher Scientific Human PEAR1 Synthetic Peptide
인간 PEAR1 단백질의 C-말단 16 아미노산 서열에 해당하는 합성 펩타이드입니다. PA5-21057 항체의 블로킹 펩타이드로 사용 가능합니다. 정제된 액상 형태로 제공되며, PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide를 포함합니다. -20°C에서 보관합니다.
- 카탈로그번호
- PEP1171
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human PEAR1.
PEP-1171 can be used as a blocking peptide with polyclonal antibody PA5-21057.
Target Information
Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an αIIbβ3 antagonist that also inhibits platelet aggregation.
Recent studies have indicated that genetic variations in PEAR1 may be associated with enhanced agonist-induced platelet aggregation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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