Thermo Fisher Scientific PRKD3 Monoclonal Antibody (OTI4G6), TrueMAB
PRKD3 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4G6). Western blot 및 IHC(P)에서 검증됨. Human 시료 반응성. Affinity chromatography로 정제된 액상 항체로, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 300–508 of human PRKD3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are involved in diverse cellular signaling pathways. They also serve as major receptors for phorbol esters, a class of tumor promoters. Each PKC family member has a specific expression profile and distinct role. The protein encoded by this gene is one of the PKC family members, activated by agonists of G protein-coupled receptors. It localizes to both cytoplasm and nucleus, with nuclear accumulation enhanced upon activation. This kinase can also be activated following B-cell antigen receptor (BCR) engagement, requiring intact phospholipase C gamma and other PKC family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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