Thermo Fisher Scientific NCF2 Polyclonal Antibody
NCF2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관하며 -20°C에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NCF2 (Accession P19878), corresponding to amino acid residues A17–D67 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854537 |
Product Specific Information
Antibody detects endogenous levels of total NCF2.
Target Information
NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of the latent NADPH oxidase, which is necessary for superoxide production.
Defects in NCF2 cause chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2), a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill ingested microbes, leading to life-threatening bacterial and fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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