Thermo Fisher Scientific L3MBTL1 Polyclonal Antibody
L3MBTL1 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 실험에 최적화됨. 고순도 친화 크로마토그래피 정제, PBS/50% 글리세롤 저장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific L3MBTL1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human L3MBTL1 (Accession Q9Y468), corresponding to amino acid residues D452–S502 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900124 |
Product Specific Information
Antibody detects endogenous levels of total L3MBTL1.
Target Information
L3MBTL1 is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain.
L3MBTL1 localizes to condensed chromosomes in mitotic cells, and its overexpression in glioma cell lines leads to improper nuclear segregation and cytokinesis, producing multinucleated cells.
This polycomb group protein regulates gene activity via chromatin modification and specifically recognizes mono- and dimethyllysine residues on target proteins, functioning as a reader of post-translational modifications.
Alternatively spliced transcript variants encoding different isoforms of the L3MBTL1 gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-115488_L3MBTL1_Q9Y468-5_Rabbit.svg / PA5-115488_L3MBTL1_Q9Y468-5_Rabbit_PDP.jpeg)
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