Thermo Fisher Scientific SHP2 Recombinant Rabbit Monoclonal Antibody (23GB2665)
SHP2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. HEK293F 시스템에서 발현되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 인체 반응성이 뛰어나며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2665 |
| Immunogen | A synthesized peptide derived from human SHP2 (525–593AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains, which serve as phospho-tyrosine binding domains and mediate substrate interactions. It is widely expressed in most tissues and plays a regulatory role in diverse signaling events, including mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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