Thermo Fisher Scientific Laminin alpha-2 Monoclonal Antibody (CL3450)
Laminin alpha-2 단백질을 특이적으로 인식하는 mouse monoclonal antibody입니다. Western blot 및 IHC(P)에서 검증되었으며, 인간, 마우스, 랫트 시료에 반응합니다. 단백질 A로 정제된 액상 형태로, 장기 보관 시 -20°C에서 보관 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL3450 |
| Immunogen | Recombinant protein corresponding to Human Laminin alpha-2 (amino acids 2111–2242) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637271 |
Product Specific Information
Immunogen sequence:
DKLKPIKELE DNLKKNISEI KELINQARKQ ANSIKVSVSS GGDCIRTYKP EIKKGSYNNI VVNVKTAVAD NLLFYLGSAK FIDFLAIEMR KGKVSFLWDV GSGVGRVEYP DLTIDDSYWY RIVASRTGRN GTAntigen sequence identity:
Mouse – 96%, Rat – 98%Epitope information:
Binds to an epitope located within the peptide sequence DKLKPIKELEDNLKK as determined by overlapping synthetic peptides.
Target Information
Laminin is a non-collagenous protein of basement membranes. It has a cross-like structure with one long arm (~400 kDa) and three short arms (~200 kDa). Antibodies to laminin localize specifically in basement membranes, showing strong reactivity in the lamina lucida adjacent to the cell membrane. Laminin binds to type IV collagen and plays an important role in cell adhesion and attachment both in vivo and in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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