Thermo Fisher Scientific ABCA6 Polyclonal Antibody
ABCA6 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 친화 크로마토그래피로 정제된 액상 항체입니다. PBS/glycerol 완충액에 보관하며 -20°C에서 저장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:50–1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from mouse Abca6 (Accession Q8K441), corresponding to amino acid residues L1589–A1609. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853709 |
Product Specific Information
Antibody detects endogenous levels of total Abca6.
Target Information
The ATP-binding cassette (ABC) superfamily comprises transmembrane proteins involved in energy-dependent transport of various substrates across membranes.
ABCA6 is a 1,617-amino acid protein belonging to the ABC transporter family. It is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis.
ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing. It is present at the highest levels in adult liver, with significant expression in adult tissues and fetal lung, kidney, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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