Thermo Fisher Scientific HMGCR Polyclonal Antibody
HMGCR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간, 생쥐, 랫드 반응성. 액상 형태, 1 mg/mL 농도, -20°C 보관. 콜레스테롤 생합성 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HMGCR (Accession P04035), corresponding to amino acid residues E19–R69 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854547 |
Product Specific Information
Antibody detects endogenous levels of total HMGCR.
Target Information
3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, essential for cholesterol and isoprenoid biosynthesis. It catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in cholesterol production. HMGCR is the primary target of statin drugs used to lower cholesterol and reduce cardiovascular disease risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-106883_HMGCR_P04035-1_Rabbit.svg, PA5-106883_HMGCR_P04035-1_Rabbit_PDP.jpeg)
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