Thermo Fisher Scientific PON1 Polyclonal Antibody
Thermo Fisher Scientific의 PON1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도(>95%) 제품으로, 액상 형태이며 PBS 기반 저장용액에 포함되어 있습니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human PON1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804055 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The paraoxonase (PON) gene family in humans includes PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is primarily synthesized in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism may contribute to neurodegeneration and is considered an independent risk factor for Parkinson’s disease.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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