Thermo Fisher Scientific UGT8 Polyclonal Antibody
UGT8 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간·마우스·랫트 반응성. 항원 친화 크로마토그래피로 정제되어 >95% 순도. 장기 보관 시 -20°C에서 안정적.
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Thermo Fisher Scientific UGT8 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in human UGT8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553994 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 61 kDa.
Purity is >95% by SDS-PAGE.
Target Information
UGT8 (UDP-galactose-ceramide galactosyltransferase, 2-hydroxyacylsphingosine 1-beta-galactosyltransferase) is a 541 amino acid, single-pass membrane protein of the UDP-glycosyltransferase family.
UGT8 is primarily involved in sphingolipid metabolism and galactosylceramide biosynthesis.
Elevated expression of UGT8 has been correlated with increased risk of lung metastases in breast cancer patients, suggesting its potential as a prognostic marker for tumor aggressiveness.
UGT8 is ubiquitously expressed, with highest levels in the central and peripheral nervous systems, and is up-regulated in breast cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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