Thermo Fisher Scientific HBEGF Polyclonal Antibody
Human HBEGF에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS 기반 버퍼와 40% 글리세롤 함유. 연구용으로 EGFR 관련 신호 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human HBEGF. Recombinant protein control fragment (Product #RP-101213). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856780 |
Product Specific Information
Immunogen sequence:
IHGECKYVKE LRAPSCICHP GYHGERCHGL SLPVENRLYT YDHTTI
Target Information
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2, and ERBB4. It is required for normal cardiac valve formation and heart function. HBEGF promotes smooth muscle cell proliferation and may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts but not endothelial cells. It binds EGFR with higher affinity than EGF and is a more potent mitogen for smooth muscle cells. It also acts as a diphtheria toxin receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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