Thermo Fisher Scientific UMPS Polyclonal Antibody
Thermo Fisher Scientific의 UMPS Polyclonal Antibody는 인간 UMPS 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. WB, IHC, ICC/IF에 적합하며 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human UMPS (aa 398–447) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609504 |
Product Specific Information
Peptide sequence:
VGFISGSRVS MKPEFLHLTP GVQLEAGGDN LGQQYNSPQE VIGKRGSDII
Sequence homology:
Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 75%
Target Information
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway.
- The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase, converting orotic acid to orotidine-5'-monophosphate.
- The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase, converting orotidine-5'-monophosphate to uridine monophosphate.
Defects in this gene cause hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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