Thermo Fisher Scientific MEF2D Polyclonal Antibody
Rabbit polyclonal antibody targeting human MEF2D for Western blot applications. Recognizes MEF2D protein involved in muscle and neuronal differentiation. Affinity-purified, liquid form, stored at -20°C. For research use only.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human MEF2D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607820 |
Product Specific Information
- Peptide sequence: GDGLSSPAGG SYETGDRDDG RGDFGPTLGL LRPAPEPEAE GSAVKRMRLD
- Sequence homology: Cow: 100%; Dog: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Target Information
MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. These proteins regulate muscle and neuronal cell differentiation and development, and are controlled by class II histone deacetylases.
Fusions of MEF2D with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) have been identified in an acute lymphoblastic leukemia cell line, suggesting a possible role in leukemogenesis.
The protein may also be associated with Parkinson’s disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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