Thermo Fisher Scientific Mist1 Polyclonal Antibody
인간 Mist1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS와 글리세롤 버퍼로 안정화되어 장기 보관 가능.
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Thermo Fisher Scientific Mist1 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BHLHA15. Recombinant protein control fragment (Product #RP-99943). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791035 |
Product Specific Information
Immunogen sequence:
AKNYIKSLTA TILTMSSSRL PGLEGPGPKL YQHYQQQQQV AGGALGATEA QPQGHLQRYS TQIHSFREG
Target Information
Mist1 plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. It may also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Mist1 serves as a key regulator of acinar cell function, stability, and identity. It is required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. Mist1 may function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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