Thermo Fisher Scientific CYP4F11 Polyclonal Antibody
CYP4F11 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. Human 시료 반응성, 항원 친화 정제, 액상 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–235 of Human CYP4F11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548258 |
Product Specific Information
- Recommended positive control: HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
CYP4F11 is an isoform of the cytochrome P450 4F protein, mainly expressed in human liver, followed by kidney, heart, and skeletal muscle.
It contains 524 amino acid residues sharing 80.0%, 82.3%, and 79.2% identity with CYP4F2, CYP4F3, and CYP4F8, respectively.
CYP4F11 exhibits catalytic activity toward endogenous eicosanoids and certain clinically relevant drugs, and can metabolize large molecules such as erythromycin.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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