Thermo Fisher Scientific CHST14 Polyclonal Antibody
CHST14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액 형태로 제공. 인간 시료에 반응하며 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: –
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
- Publications: –
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CHST14 (Recombinant protein control fragment, Product #RP-105539) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2664116 |
Product Specific Information
Immunogen sequence:
GILAEMKPLPL HPPGREGTAW RGKAPKPGGL SLRAGDADLQ VRQDVRNRTL RAVCGQPGMP RDPWDLPV
Highest antigen sequence identity to the following orthologs:
- Mouse: 81%
- Rat: 78%
Target Information
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-O-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of β1,4-linked GalNAc that is substituted with an α-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA- sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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