Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 고순도의 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–133 of human IFITM3 (NP_0663622) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.76 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805257 |
Product Specific Information
- Immunogen sequence:
MNHTVQTFFS PVNSGQPPNY EMLKEEHEVA VLGAPHNPAP PTSTVIHIRS ETSVPDHVVW SLFNTLFMNP CCLGFIAFAY SVKSRDRKMV GDVTGAQAYA STAKCLNIWA LILGILMTIL LIVIPVLIFQ AYG - Positive Samples: HeLa
- Cellular Location: Cell membrane, Late endosome membrane, Lysosome membrane, Single-pass type II membrane protein
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and II interferons and contain interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins are involved in cellular anti-proliferative activities, homotypic cell adhesion, and may play roles in carcinogenesis.
IFITM3 is a 133 amino acid protein localized to the membrane and is induced by IFN-α and IFN-γ. Its expression can be regulated by TEF-1, Brg-1, and Sp1.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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