Thermo Fisher Scientific C9ORF90 Polyclonal Antibody, MaxPab
C9ORF90(NAIF1) 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 유래 항원으로 제작되었으며, 액상 형태로 제공되고 PBS 버퍼에 보존제가 없습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C9orf90 (NP_931045, 1 a.a. ~ 327 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG GGSGGGGPAV APVLLTPMQQ RICNLLGEAT IISLPSTTEI HPVALGPSAT AAAATVTLTQ IPTETTYHTL EEGVVEYCTA EAPPPLPPET PVDMMAQHAD TSVKPQALKS RIALNSAKLI QEQRVTNLHV KEIAQHLEQQ NDLLQMIRRS QEVQACAQER QAQAMEGTQA ALSVLIQVLR PMIKDFRRYL QSNTANPAPA SDPGQVAQNG QPDSIIQ
Target Information
Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region.
NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken, and frog, and shares no obvious homology to any known genes or proteins.
NAIF1 is predominantly localized in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis, decreases mitochondrial membrane potential, and activates caspase-3.
In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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