Thermo Fisher Scientific C9ORF90 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000 dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG GGSGGGGPAV APVLLTPMQQ RICNLLGEAT IISLPSTTEI HPVALGPSAT AAAATVTLTQ IPTETTYHTL EEGVVEYCTA EAPPPLPPET PVDMMAQHAD TSVKPQALKS RIALNSAKLI QEQRVTNLHV KEIAQHLEQQ NDLLQMIRRS QEVQACAQER QAQAMEGTQA ALSVLIQVLR PMIKDFRRYL QSNTANPAPA SDPGQVAQNG QPDSIIQ

Target Information

Human NAIF1 is located on chromosome 9q34.11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region.
NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken, and frog, and shares no obvious homology to any known genes or proteins.
NAIF1 is predominantly localized in the nucleus. Overexpression of NAIF1 inhibits cell growth and induces apoptosis, decreases mitochondrial membrane potential, and activates caspase-3.
In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.