Thermo Fisher Scientific PPP3CC Polyclonal Antibody
Thermo Fisher Scientific의 PPP3CC 폴리클로날 항체는 인간 시료에 반응하며, ICC/IF 실험에 최적화된 고순도 항체입니다. Affinity chromatography로 정제되었으며, 0.3 mg/mL 농도의 액상 형태로 제공됩니다. Calcineurin 관련 연구용으로 사용되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence, range: 275–312 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3091767 |
Product Specific Information
- Immunogen sequence: RAHEAQDAGY RMYRKSQATG FPSLITIFSA PNYLDVYN
- Antigen sequence identity: Mouse 97%; Rat 97%
Target Information
Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biological activities as a Ca²⁺-dependent modifier of phosphorylation status. In testis, sperm motility is thought to be controlled by cAMP-dependent phosphorylation, and a unique form of calcineurin appears to be associated with the flagellum.
The calcineurin holoenzyme consists of catalytic and regulatory subunits of 60 and 18 kD, respectively. Three genes—calcineurin A-alpha, calcineurin A-beta, and calcineurin A-gamma (CALNA3)—encode the catalytic subunit. These genes are identified in humans, mice, and rats, showing high conservation (90–95% amino acid identity).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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