Thermo Fisher Scientific CD266 Polyclonal Antibody
CD266(TWEAK Receptor/Fn14)에 특이적인 Rabbit Polyclonal Antibody로, WB 및 IP에 적합. 다양한 종(Bovine, Human, Mouse, Rat)에 반응. 고순도 항원 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Thermo Fisher Scientific CD266 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxy terminus of the TWEAK Receptor/Fn14 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 197 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 50% glycerol, 100µg/mL BSA, 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984051 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in transformed cell lines. A receptor for TWEAK, known as TweakR, was isolated by expression cloning from a HUVEC cell cDNA library.
TweakR is a small protein belonging to the TNF receptor superfamily and can initiate a proliferative signal by binding to TRAF1, TRAF2, and TRAF3.
TweakR mRNA is upregulated during tissue regeneration in the aorta and liver and may play a role in vascular cell migration and angiogenesis.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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