Thermo Fisher Scientific FPGT Polyclonal Antibody
Thermo Fisher Scientific의 FPGT Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 다양한 면역실험(WB, IHC, ICC, ELISA)에 적합합니다. KLH 결합 합성 펩타이드 면역원으로 제작된 Rabbit IgG 폴리클로날 항체로, 고순도 Protein A 정제 및 안정적 액상 형태로 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FPGT, amino acids 251–350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
L-fucose is a key sugar component in glycoproteins and other complex carbohydrates, playing roles in cellular recognition and signaling. The fucosyl donor for fucosylated oligosaccharides is GDP-beta-L-fucose. There are two pathways for GDP-fucose biosynthesis:
- The major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose.
- The alternate pathway, active in mammalian tissues such as liver and kidney, functions as a salvage route to reutilize L-fucose from glycoprotein and glycolipid turnover.
In this pathway, L-fucose is phosphorylated to beta-L-fucose-1-phosphate, which then condenses with GTP via fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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